contained use

- any operation involving organisms which are controlled by physical barriers or a combination of physical and/or biological barriers which limit their contact with, or their impacts on, the potentially receiving environment, which includes humans. [BSWG/2/5: UNEP International Technical Guidelines for Safety in Biotechnology] - any operation in which microorganisms are genetically modified or in which such genetically modified microorganisms are cultured, stored, used, transported, destroyed or disposed of and for which physical barriers, or a combination of physical barriers together with chemical and/or biological barriers are used to limit their contact with the general population and the environment. [BSWG/2/5: Council Directive 90/219/EEC on the contained use of genetically modified microorganisms]